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α6β1- and αV-integrins are required for long-term self-renewal of murine embryonic stem cells in the absence of LIF
BACKGROUND: The growth properties and self-renewal capacity of embryonic stem (ES) cells are regulated by their immediate microenvironment such as the extracellular matrix (ECM). Integrins, a central family of cellular ECM receptors, have been implicated in these processes but their specific role in...
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| Veröffentlicht in: | BMC Cell Biol |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348401/ https://ncbi.nlm.nih.gov/pubmed/25886986 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-015-0051-y |
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