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The use of SC1 (Pluripotin) to Support mESC Self-renewal in the Absence of LIF

Mouse embryonic stem (ES) cells are conventionally cultured with Leukemia Inhibitory Factor (LIF) to maintain self-renewal.(1) However, LIF is expensive and activation of the LIF/JAK/STAT3 pathway is not absolutely required to maintain the self-renewal state.(2) The SC1 small molecule may be an econ...

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מידע ביבליוגרפי
Main Authors: Xiong, Wen, Gao, Yan, Cheng, Xun, Martin, Charles, Wu, Dongmei, Yao, Shuyuan, Kim, Min-Ju, Liu, Yang
פורמט: Artigo
שפה:Inglês
יצא לאור: MyJove Corporation 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3157853/
https://ncbi.nlm.nih.gov/pubmed/19924098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/1550
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