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Systemically administered brain-targeted nanoparticles transport peptides across the blood–brain barrier and provide neuroprotection
Although growth factors and anti-apoptotic peptides have been shown to be neuroprotective in stroke models, translation of these experimental findings to clinic is hampered by limited penetration of peptides to the brain. Here, we show that a large peptide like the basic fibroblast growth factor (bF...
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| Publicado no: | J Cereb Blood Flow Metab |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348388/ https://ncbi.nlm.nih.gov/pubmed/25492116 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.220 |
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