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Evidence of more ion channels inhibited by celecoxib: K(V)1.3 and L-type Ca(2+) channels

BACKGROUND: Celecoxib, a selective inhibitor of cyclooxygenase-2, can directly modulate many voltage-activated potassium, sodium and calcium channels and alter functioning of excitable cells. The inhibitory and facilitating effects of celecoxib on ion channels occur at low micromolar concentrations,...

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Detalhes bibliográficos
Publicado no:BMC Res Notes
Main Authors: Frolov, Roman V, Singh, Satpal
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348164/
https://ncbi.nlm.nih.gov/pubmed/25889233
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13104-015-1023-1
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