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Inhibition of Ion Channels and Heart Beat in Drosophila by Selective COX-2 Inhibitor SC-791
Recent findings suggest that modulation of ion channels might be implicated in some of the clinical effects of coxibs, selective inhibitors of cyclooxygenase-2 (COX-2). Celecoxib and its inactive analog 2,5-dimethyl-celecoxib, but not rofecoxib, can suppress or augment ionic currents and alter funct...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368905/ https://ncbi.nlm.nih.gov/pubmed/22701705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038759 |
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