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Inhibition of Ion Channels and Heart Beat in Drosophila by Selective COX-2 Inhibitor SC-791

Recent findings suggest that modulation of ion channels might be implicated in some of the clinical effects of coxibs, selective inhibitors of cyclooxygenase-2 (COX-2). Celecoxib and its inactive analog 2,5-dimethyl-celecoxib, but not rofecoxib, can suppress or augment ionic currents and alter funct...

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Detalhes bibliográficos
Main Authors: Frolov, Roman V., Singh, Satpal
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368905/
https://ncbi.nlm.nih.gov/pubmed/22701705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038759
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