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Conditional Trimerization and Lytic Activity of HIV-1 gp41 Variants containing the Membrane-Associated Segments
Fusion of host and viral membranes is a critical step during infection by membrane-bound viruses. The HIV-1 glycoproteins gp120 (surface subunit) and gp41 (fusion subunit) represent the prototypic system for studying this process; in the prevailing model, the gp41 ectodomain forms a trimeric six-hel...
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Publicado no: | Biochemistry |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4348151/ https://ncbi.nlm.nih.gov/pubmed/25658332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi501376f |
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