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Exploiting the head and neck cancer oncogenome: Widespread PI3K-mTOR pathway alterations and novel molecular targets

Two studies published in this issue of Cancer Discovery describe the emerging mutational landscape of head and neck squamous cell carcinomas (HNSCC) and their genomic and epigenetic alterations, thus identifying novel actionable cancer drivers and predictive biomarkers for targeted therapies. Most g...

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Detalles Bibliográficos
Publicado en:Cancer Discov
Autores principales: Iglesias-Bartolome, Ramiro, Martin, Daniel, Gutkind, J. Silvio
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4348071/
https://ncbi.nlm.nih.gov/pubmed/23847349
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-13-0239
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