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Can the DNA Damage Response be Harnessed to Modulate Atherosclerotic Plaque Phenotype?

Gray et al(1) describe studies to examine smooth muscle cell (SMC)-selective effects of acceleration or inhibition of double-strand DNA break repair on atherosclerotic lesion phenotype in the ApoE-/- mouse model. Markers of the DNA damage response (DDR) and expression of DNA repair enzymes are both...

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Detalhes bibliográficos
Publicado no:Circ Res
Main Authors: Razani, Babak, Raines, Elaine W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347866/
https://ncbi.nlm.nih.gov/pubmed/25722437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.115.305922
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