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Spatial and Cellular Characterization of mTORC1 Activation after Spinal Cord Injury Reveals Biphasic Increase Mainly Attributed to Microglia/Macrophages

Mechanistic target of rapamycin complex 1 (mTORC1) is an intracellular kinase complex that regulates energy homeostasis and transcription. Modulation of mTORC1 has proven beneficial in experimental spinal cord injury, making this molecular target a candidate for therapeutic intervention in spinal co...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Kjell, Jacob, Codeluppi, Simone, Josephson, Anna, Abrams, Mathew B.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347463/
https://ncbi.nlm.nih.gov/pubmed/24576152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bpa.12135
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