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Imatinib Enhances Functional Outcome after Spinal Cord Injury

We investigated whether imatinib (Gleevec®, Novartis), a tyrosine kinase inhibitor, could improve functional outcome in experimental spinal cord injury. Rats subjected to contusion spinal cord injury were treated orally with imatinib for 5 days beginning 30 minutes after injury. We found that imatin...

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Detalhes bibliográficos
Main Authors: Abrams, Mathew B., Nilsson, Ingrid, Lewandowski, Sebastian A., Kjell, Jacob, Codeluppi, Simone, Olson, Lars, Eriksson, Ulf
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378614/
https://ncbi.nlm.nih.gov/pubmed/22723886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038760
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