Seroreactivity to a Large Panel of Field-Derived Plasmodium falciparum Apical Membrane Antigen 1 and Merozoite Surface Protein 1 Variants Reflects Seasonal and Lifetime Acquired Responses to Malaria

Parasite antigen diversity poses an obstacle to developing an effective malaria vaccine. A protein microarray containing Plasmodium falciparum apical membrane antigen 1 (AMA1, n = 57) and merozoite surface protein 1 19-kD (MSP1(19), n = 10) variants prevalent at a malaria vaccine testing site in Ban...

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Published in:Am J Trop Med Hyg
Main Authors: Bailey, Jason A., Pablo, Jozelyn, Niangaly, Amadou, Travassos, Mark A., Ouattara, Amed, Coulibaly, Drissa, Laurens, Matthew B., Takala-Harrison, Shannon L., Lyke, Kirsten E., Skinner, Jeff, Berry, Andrea A., Jasinskas, Algis, Nakajima-Sasaki, Rie, Kouriba, Bourema, Thera, Mahamadou A., Felgner, Philip L., Doumbo, Ogobara K., Plowe, Christopher V.
Format: Artigo
Language:Inglês
Published: The American Society of Tropical Medicine and Hygiene 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347399/
https://ncbi.nlm.nih.gov/pubmed/25294612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4269/ajtmh.14-0140
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