Inflammation and ER Stress Regulate Branched-Chain Amino Acid Uptake and Metabolism in Adipocytes

Inflammation plays a critical role in the pathology of obesity-linked insulin resistance and is mechanistically linked to the effects of macrophage-derived cytokines on adipocyte energy metabolism, particularly that of the mitochondrial branched-chain amino acid (BCAA) and tricarboxylic acid (TCA) p...

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Vydáno v:Mol Endocrinol
Hlavní autoři: Burrill, Joel S., Long, Eric K., Reilly, Brian, Deng, Yingfeng, Armitage, Ian M., Scherer, Philipp E., Bernlohr, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Endocrine Society 2015
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347289/
https://ncbi.nlm.nih.gov/pubmed/25635940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2014-1275
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