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TACI deficiency enhances antibody avidity and clearance of an intestinal pathogen
The transmembrane activator and calcium-modulating cyclophilin ligand interactor (TACI) controls differentiation of long-lived plasma cells, and almost 10% of individuals with common variable immunodeficiency (CVID) express either the C104R or A181E variants of TACI. These variants impair TACI funct...
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| Publicado no: | J Clin Invest |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347253/ https://ncbi.nlm.nih.gov/pubmed/25271628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74428 |
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