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TRPM2 mediates ischemic kidney injury and oxidant stress through RAC1

Ischemia is a leading cause of acute kidney injury. Kidney ischemia is associated with loss of cellular ion homeostasis; however, the pathways that underlie ion homeostasis dysfunction are poorly understood. Here, we evaluated the nonselective cation channel transient receptor potential melastatin 2...

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Detalles Bibliográficos
Publicado en:J Clin Invest
Main Authors: Gao, Guofeng, Wang, Weiwei, Tadagavadi, Raghu K., Briley, Nicole E., Love, Michael I., Miller, Barbara A., Reeves, W. Brian
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4347231/
https://ncbi.nlm.nih.gov/pubmed/25295536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76042
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