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Endometrial VEGF induces placental sFLT1 and leads to pregnancy complications
There is strong evidence that overproduction of soluble fms-like tyrosine kinase-1 (sFLT1) in the placenta is a major cause of vascular dysfunction in preeclampsia through sFLT1-dependent antagonism of VEGF. However, the cause of placental sFLT1 upregulation is not known. Here we demonstrated that i...
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Publicado no: | J Clin Invest |
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Main Authors: | , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4347223/ https://ncbi.nlm.nih.gov/pubmed/25329693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI76864 |
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