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Caveolin-1 prevents sustained angiotensin II-induced resistance artery constriction and obesity-induced high blood pressure

The type 1 angiotensin II (ANG II) receptor (AT(1)R) undergoes internalization following stimulation by ANG II. Internalization reduces cell surface AT(1)Rs, and it is required for AT(1)R resensitization. In this process AT(1)R may interact with caveolin-1 (Cav1), the main scaffolding protein of cav...

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Опубликовано в: :Am J Physiol Heart Circ Physiol
Главные авторы: Czikora, Istvan, Feher, Attila, Lucas, Rudolf, Fulton, David J. R., Bagi, Zsolt
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346763/
https://ncbi.nlm.nih.gov/pubmed/25527780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00649.2014
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