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Caveolin-1 limits the contribution of BK(Ca) channel to EDHF-mediated arteriolar dilation: implications in diet-induced obesity

AIMS: Caveolin-1 (Cav-1) interacts with large conductance Ca(2+)-activated potassium channels (BKCa) and likely exerts a negative regulatory effect on the channel activity. We investigated the role of Cav-1 in modulating BK(Ca) channel-mediated, endothelium-derived hyperpolarizing factor (EDHF)-depe...

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Hlavní autoři: Feher, Attila, Rutkai, Ibolya, Beleznai, Timea, Ungvari, Zoltan, Csiszar, Anna, Edes, Istvan, Bagi, Zsolt
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2920808/
https://ncbi.nlm.nih.gov/pubmed/20299334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq088
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