Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat

We have reported that a reduction in renal production of 20-HETE contributes to development of hypertension in Dahl salt-sensitive (SS) rats. The present study examined whether 20-HETE production is also reduced in the cerebral vasculature of SS rats and whether this impairs the myogenic response an...

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Pubblicato in:Am J Physiol Regul Integr Comp Physiol
Autori principali: Fan, Fan, Geurts, Aron M., Murphy, Sydney R., Pabbidi, Mallikarjuna R., Jacob, Howard J., Roman, Richard J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2014
Soggetti:
Cardiovascular and Renal Integration
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346760/
https://ncbi.nlm.nih.gov/pubmed/25540098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00256.2014
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