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Over-Expression of Telomere Binding Factors (TRF1 & TRF2) in Renal Cell Carcinoma and Their Inhibition by Using SiRNA Induce Apoptosis, Reduce Cell Proliferation and Migration Invitro

Telomere binding factors viz. TRF1 and TRF2 are a part of sheltrin complex that are present exclusively at the ends of chromosomes. These factors play an important role in maintaining chromosomal integrity at the ends. However, their status and role are not clear in renal cell carcinoma (RCC). There...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Pal, Deeksha, Sharma, Ujjawal, Singh, Shrawan Kumar, Kakkar, Nandita, Prasad, Rajendra
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346586/
https://ncbi.nlm.nih.gov/pubmed/25730259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115651
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