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E3 ubiquitin ligase Siah-1 downregulates synaptophysin expression under high glucose and hypoxia

Background: Diabetes is proved to be one of the independent risk factors for cognitive dysfunction. The pathophysiologic changes caused by diabetes including hyperglycemia and tissue hypoxia may contribute greatly to cognitive decline. In the present study, we demonstrate E3 Ubiquitin Ligase Siah-1...

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Bibliografiska uppgifter
I publikationen:Am J Transl Res
Huvudupphovsmän: Zhao, Yanxin, Li, Qiang, Jin, Aiping, Cui, Mei, Liu, Xueyuan
Materialtyp: Artigo
Språk:Inglês
Publicerad: e-Century Publishing Corporation 2015
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346520/
https://ncbi.nlm.nih.gov/pubmed/25755825
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