T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif.

The T-cell antigen CD28 provides a costimulatory signal that is required for T-cell proliferation. T-cell receptor zeta/CD3 engagement without CD28 ligation leads to a state of nonresponsiveness/anergy, thereby implicating CD28 in the control of peripheral tolerance to foreign antigens or tumors. A...

Deskribapen osoa

Xehetasun bibliografikoak

Argitaratua izan da:	Proc Natl Acad Sci U S A
Egile Nagusiak:	Prasad, K V, Cai, Y C, Raab, M, Duckworth, B, Cantley, L, Shoelson, S E, Rudd, C E
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	National Academy of Sciences 1994
Gaiak:	Research Article
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43465/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8146197/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.7.2834
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!