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Ligand-based virtual screening identifies a family of selective cannabinoid receptor 2 agonists

The cannabinoid receptor 2 (CB(2)R) has been linked with the regulation of inflammation, and selective receptor activation has been proposed as a target for the treatment of a range of inflammatory diseases such as atherosclerosis and arthritis. In order to identify selective CB(2)R agonists with ap...

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Bibliographic Details
Published in:Bioorg Med Chem
Main Authors: Gianella-Borradori, Matteo, Christou, Ivy, Bataille, Carole J.R., Cross, Rebecca L., Wynne, Graham M., Greaves, David R., Russell, Angela J.
Format: Artigo
Language:Inglês
Published: Elsevier Science 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346271/
https://ncbi.nlm.nih.gov/pubmed/25487422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2014.11.002
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