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The Core Promoter and Redox-sensitive Cis-elements as Key Targets for Inactivation of the Lysyl Oxidase Gene by Cadmium

Exposure of humans to cadmium (Cd) either from environmental contamination or from cigarette smoke, often induces lung emphysema and cancers. Lysyl oxidase (LOX), a copper-dependent enzyme essential for crosslinking of the extracellular matrix, displays antagonistic effects on emphysema and cancer p...

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Bibliografiske detaljer
Udgivet i:J Nat Sci
Main Authors: Li, Jianmin, Cheng, Guang, Zheng, Maoguen, Zhao, Yinzhi, Zhou, Jing, Li, Wande
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346169/
https://ncbi.nlm.nih.gov/pubmed/25741534
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