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Localization and activity of lysyl oxidase within nuclei of fibrogenic cells

Lysyl oxidase (EC 1.4.3.13) oxidizes peptidyl lysine to peptidyl aldehyde residues within collagen and elastin, thus initiating formation of the covalent cross-linkages that insolubilize these extracellular proteins. Recent findings raise the possibility that this enzyme may also function intracellu...

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Autors principals: Li, Wande, Nellaiappan, Kaliappanadar, Strassmaier, Timothy, Graham, Lila, Thomas, Kathleen M., Kagan, Herbert M.
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences of the USA 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24221/
https://ncbi.nlm.nih.gov/pubmed/9371758
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