GLYCEMIC REGULATION AND INSULIN SECRETION ARE ABNORMAL IN CYSTIC FIBROSIS PIGS DESPITE SPARING OF ISLET CELL MASS

Diabetes is a common and significant comorbidity in cystic fibrosis (CF). The pathogenesis of CF-related diabetes (CFRD) is incompletely understood. Because exocrine pancreatic disease is similar between humans and pigs with CF, the CF pig model has the potential to contribute significantly to the u...

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Veröffentlicht in:Clin Sci (Lond)
Hauptverfasser: Uc, Aliye, Olivier, Alicia K., Griffin, Michelle A., Meyerholz, David K., Yao, Jianrong, Abu-El-Haija, Maisam, Buchanan, Katherine M., Vanegas Calderón, Oriana G., Abu-El-Haija, Marwa, Pezzulo, Alejandro A., Reznikov, Leah R., Hoegger, Mark J., Rector, Michael V., Ostedgaard, Lynda S., Taft, Peter J., Gansemer, Nick D., Ludwig, Paula S., Hornick, Emma E., Stoltz, David A., Ode, Katie L., Welsh, Michael J., Engelhardt, John F., Norris, Andrew W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346161/
https://ncbi.nlm.nih.gov/pubmed/25142104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/CS20140059
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