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Commensal bacteria drive endogenous transformation and tumour stem cell marker expression through a bystander effect
OBJECTIVE: Commensal bacteria and innate immunity play a major role in the development of colorectal cancer (CRC). We propose that selected commensals polarise colon macrophages to produce endogenous mutagens that initiate chromosomal instability (CIN), lead to expression of progenitor and tumour st...
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| Publicado no: | Gut |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMJ Publishing Group
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4345889/ https://ncbi.nlm.nih.gov/pubmed/24906974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307213 |
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