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Rapid depletion of B lymphocytes by ultra-low-dose rituximab delivered intrathecally
OBJECTIVE: We are conducting an open-label phase 1b study on the efficacy of intrathecal (IT) administration of rituximab, provided via an Ommaya reservoir, for the treatment of progressive multiple sclerosis (PMS). The objective of this initial study was to monitor B lymphocytes in peripheral blood...
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| Publicado no: | Neurol Neuroimmunol Neuroinflamm |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Lippincott Williams & Wilkins
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4345631/ https://ncbi.nlm.nih.gov/pubmed/25745637 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/NXI.0000000000000079 |
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