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Autism-associated mutation inhibits protein kinase C-mediated neuroligin-4X enhancement of excitatory synapses

Autism spectrum disorders (ASDs) comprise a highly heritable, multifarious group of neurodevelopmental disorders, which are characterized by repetitive behaviors and impairments in social interactions. Point mutations have been identified in X-linked Neuroligin (NLGN) 3 and 4X genes in patients with...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Bemben, Michael A., Nguyen, Quynh-Anh, Wang, Tongguang, Li, Yan, Nicoll, Roger A., Roche, Katherine W.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345621/
https://ncbi.nlm.nih.gov/pubmed/25675530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1500501112
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