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Proteome response at the edge of protein aggregation

Proteins adopt defined structures and are crucial to most cellular functions. Their misfolding and aggregation is associated with numerous degenerative human disorders such as type II diabetes, Huntington's or Alzheimer's diseases. Here, we aim to understand why cells promote the formation...

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Detalhes bibliográficos
Publicado no:Open Biol
Main Authors: Sanchez de Groot, Natalia, Gomes, Ricardo A., Villar-Pique, Anna, Babu, M. Madan, Coelho, Ana Varela, Ventura, Salvador
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345283/
https://ncbi.nlm.nih.gov/pubmed/25673330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.140221
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