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Using bacterial inclusion bodies to screen for amyloid aggregation inhibitors
BACKGROUND: The amyloid-β peptide (Aβ42) is the main component of the inter-neuronal amyloid plaques characteristic of Alzheimer's disease (AD). The mechanism by which Aβ42 and other amyloid peptides assemble into insoluble neurotoxic deposits is still not completely understood and multiple fac...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2012
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495732/ https://ncbi.nlm.nih.gov/pubmed/22553999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2859-11-55 |
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