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Nutrient-stimulated insulin secretion in mouse islets is critically dependent on intracellular pH

BACKGROUND: Many mechanistic steps underlying nutrient-stimulated insulin secretion (NSIS) are poorly understood. The influence of intracellular pH (pH(i)) on insulin secretion is widely documented, and can be used as an investigative tool. This study demonstrates previously unknown effects of pH(i)...

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Detalhes bibliográficos
Publicado no:BMC Endocr Disord
Main Authors: Gunawardana, Subhadra C, Rocheleau, Jonathan V, Head, W Steven, Piston, David W
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2004
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434517/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15193158/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1472-6823-4-1
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