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Roles of nicotinic acetylcholine receptor β subunit cytoplasmic loops in acute desensitization and single channel features
To evaluate physiological roles of the large, second cytoplasmic loops (C2) situated between the M3 and M4 transmembrane domains of nicotinic acetylcholine receptor (nAChR) subunits. We have constructed chimeric β2 (β2χ) and β4 (β4χ) subunits in which the “nested” C2 domains (but not the “proximal”...
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| Veröffentlicht in: | Neuroscience |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344923/ https://ncbi.nlm.nih.gov/pubmed/25536046 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2014.12.016 |
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