Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma

Tumour-initiating cells are thought to share features with normal somatic stem cells. In mice, stem cells at the ovarian hilum have been shown to express the stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1A1), and are prone to malignant transformation. The potential relevance of this findi...

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Vydáno v:Mod Pathol
Hlavní autoři: Chui, M. Herman, Wang, Yihong, Wu, Ren-Chin, Seidman, Jeffrey, Kurman, Robert J., Wang, Tian-Li, Shih, Ie-Ming
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344882/
https://ncbi.nlm.nih.gov/pubmed/25216223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2014.89
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