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Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma
Tumour-initiating cells are thought to share features with normal somatic stem cells. In mice, stem cells at the ovarian hilum have been shown to express the stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1A1), and are prone to malignant transformation. The potential relevance of this findi...
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| Publié dans: | Mod Pathol |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2014
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344882/ https://ncbi.nlm.nih.gov/pubmed/25216223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2014.89 |
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