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Loss of ALDH1A1 expression is an early event in the pathogenesis of ovarian high-grade serous carcinoma

Tumour-initiating cells are thought to share features with normal somatic stem cells. In mice, stem cells at the ovarian hilum have been shown to express the stem cell marker, aldehyde dehydrogenase isoform 1 (ALDH1A1), and are prone to malignant transformation. The potential relevance of this findi...

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Detalhes bibliográficos
Publicado no:Mod Pathol
Main Authors: Chui, M. Herman, Wang, Yihong, Wu, Ren-Chin, Seidman, Jeffrey, Kurman, Robert J., Wang, Tian-Li, Shih, Ie-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344882/
https://ncbi.nlm.nih.gov/pubmed/25216223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2014.89
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