A reassessment of soluble urokinase-type plasminogen activator receptor in glomerular disease

It has been suggested that soluble urokinase receptor (suPAR) is a causative circulating factor for and a biomarker of focal and segmental glomerulosclerosis (FSGS). Here we undertook validation of these assumptions in both mouse and human models. Injection of recombinant suPAR in wild-type mice did...

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Detalhes bibliográficos
Publicado no:Kidney Int
Main Authors: Spinale, Joann M., Mariani, Laura H., Kapoor, Shiv, Zhang, Jidong, Weyant, Robert, Song, Peter X., Wong, Hetty N., Troost, Jonathan P., Gadegbeku, Crystal A., Gipson, Debbie S., Kretzler, Matthias, Nihalani, Deepak, Holzman, Lawrence B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344842/
https://ncbi.nlm.nih.gov/pubmed/25354239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2014.346
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