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Selective Blocking Effects of 4,9-Anhydrotetrodotoxin, Purified from a Crude Mixture of Tetrodotoxin Analogues, on Na(V)1.6 Channels and Its Chemical Aspects
Tetrodotoxin (TTX) is a potent neurotoxin found in a number of marine creatures including the pufferfish, where it is synthesized by bacteria and accumulated through the food chain. It is a potent and selective blocker of some types of voltage-gated Na(+) channel (Na(V) channel). 4,9-Anhydrotetrodot...
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| Publicado en: | Mar Drugs |
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| Autores principales: | , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
MDPI
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4344613/ https://ncbi.nlm.nih.gov/pubmed/25686275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13020984 |
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