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Wnt16 Attenuates TGFβ-induced Chondrogenic Transformation in Vascular Smooth Muscle

OBJECTIVE: Phenotypic plasticity of vascular smooth muscle cells (VSMCs) contributes to cardiovascular disease. Chondrocyte-like transformation of VSMCs associates with vascular calcification and underlies the formation of aortic cartilaginous metaplasia induced in mice by genetic loss of matrix Gla...

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Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Beazley, Kelly E., Nurminsky, Dmitry, Lima, Florence, Gandhi, Chintan, Nurminskaya, Maria V.
Format: Artigo
Language:Inglês
Published: 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344425/
https://ncbi.nlm.nih.gov/pubmed/25614285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304393
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