Epidermal Growth Factor Receptor Inhibition Reduces Angiogenesis via Hypoxia-Inducible Factor-1α and Notch1 in Head Neck Squamous Cell Carcinoma

Angiogenesis, a marker of cancer development, affects response to radiotherapy sensibility. This preclinical study aims to understand the receptor tyrosine kinase-mediated angiogenesis in head neck squamous cell carcinoma (HNSCC). The receptor tyrosine kinase activity in a transgenic mouse model of...

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Vydáno v:PLoS One
Hlavní autoři: Wang, Wei-Ming, Zhao, Zhi-Li, Ma, Si-Rui, Yu, Guang-Tao, Liu, Bing, Zhang, Lu, Zhang, Wen-Feng, Kulkarni, Ashok B., Sun, Zhi-Jun, Zhao, Yi-Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344331/
https://ncbi.nlm.nih.gov/pubmed/25723392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119723
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