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The nuclear matrix is a thermolabile cellular structure

Heat shock sensitizes cells to ionizing radiation, cells heated in S phase have increased chromosomal aberrations, and both Hsp27 and Hsp70 translocate to the nucleus following heat shock, suggesting that the nucleus is a site of thermal damage. We show that the nuclear matrix is the most thermolabi...

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Autors principals: Lepock, James R., Frey, Harold E., Heynen, Miriam L., Senisterra, Guillermo A., Warters, Raymond L.
Format: Artigo
Idioma:Inglês
Publicat: Cell Stress Society International 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC434391/
https://ncbi.nlm.nih.gov/pubmed/11599575
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