IL-4 abrogates T(H)17 cell-mediated inflammation by selective silencing of IL-23 in antigen-presenting cells

Interleukin 4 (IL-4) can suppress delayed-type hypersensitivity reactions (DTHRs), including organ-specific autoimmune diseases in mice and humans. Despite the broadly documented antiinflammatory effect of IL-4, the underlying mode of action remains incompletely understood, as IL-4 also promotes IL-...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Autores principales: Guenova, Emmanuella, Skabytska, Yuliya, Hoetzenecker, Wolfram, Weindl, Günther, Sauer, Karin, Tham, Manuela, Kim, Kyu-Won, Park, Ji-Hyeon, Seo, Ji Hae, Ignatova, Desislava, Cozzio, Antonio, Levesque, Mitchell P., Volz, Thomas, Köberle, Martin, Kaesler, Susanne, Thomas, Peter, Mailhammer, Reinhard, Ghoreschi, Kamran, Schäkel, Knut, Amarov, Boyko, Eichner, Martin, Schaller, Martin, Clark, Rachael A., Röcken, Martin, Biedermann, Tilo
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2015
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343151/
https://ncbi.nlm.nih.gov/pubmed/25646481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1416922112
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares