Interleukin-1 loop model for pathogenesis of Langerhans cell histiocytosis

We propose Langerhans cell histiocytosis (LCH) is an inflammatory process that is prolonged by mutations. We hypothesize that Merkel cell polyomavirus (MCPyV) infection triggers an interleukin-1 (IL-1) activation loop that underlies the pathogenesis of LCH. Langerhans cells (LCs) are antigen present...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Murakami, Ichiro, Matsushita, Michiko, Iwasaki, Takeshi, Kuwamoto, Satoshi, Kato, Masako, Nagata, Keiko, Horie, Yasushi, Hayashi, Kazuhiko, Imamura, Toshihiko, Morimoto, Akira, Imashuku, Shinsaku, Gogusev, Jean, Jaubert, Francis, Takata, Katsuyoshi, Oka, Takashi, Yoshino, Tadashi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343072/
https://ncbi.nlm.nih.gov/pubmed/25889448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-015-0092-z
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