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The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation
We originally cloned and identified murine Zizimin2 (Ziz2, Dock11) as a guanine nucleotide exchange factor (GEF) for Cdc42 and demonstrated that it activated the formation of filopodia. Since its expression pattern is restricted in immune tissues and Rho GTPases such as Cdc42 function in B cell deve...
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| Publié dans: | Immun Ageing |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BioMed Central
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4343071/ https://ncbi.nlm.nih.gov/pubmed/25729399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0028-x |
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