Marginal Zone B Cells Induce Alloantibody Formation Following RBC Transfusion

Red blood cell (RBC) alloimmunization represents a significant immunological challenge for some patients. While a variety of immune constituents likely contribute to the initiation and orchestration of alloantibodies to RBC antigens, identification of key immune factors that initiate alloantibody fo...

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Main Authors: Seema R. Patel, David R. Gibb, Kathryn Girard-Pierce, Xiaoxi Zhou, Lilian Cataldi Rodrigues, Connie M. Arthur, Ashley L. Bennett, Ryan P. Jajosky, Megan Fuller, Cheryl L. Maier, Patricia E. Zerra, Satheesh Chonat, Nicole H. Smith, Christopher A. Tormey, Jeanne E. Hendrickson, Sean R. Stowell
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-11-01
Colecção:Frontiers in Immunology
Assuntos:
marginal zone (MZ) B cells
RBC alloimmunization
follicular B cells
CD4 T cells
splenic marginal zone
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2018.02516/full
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