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The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation

We originally cloned and identified murine Zizimin2 (Ziz2, Dock11) as a guanine nucleotide exchange factor (GEF) for Cdc42 and demonstrated that it activated the formation of filopodia. Since its expression pattern is restricted in immune tissues and Rho GTPases such as Cdc42 function in B cell deve...

Полное описание

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Библиографические подробности
Опубликовано в: :Immun Ageing
Главные авторы: Matsuda, Takenori, Yanase, Shougo, Takaoka, Akinori, Maruyama, Mitsuo
Формат: Artigo
Язык:Inglês
Опубликовано: BioMed Central 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343071/
https://ncbi.nlm.nih.gov/pubmed/25729399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0028-x
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