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The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation
We originally cloned and identified murine Zizimin2 (Ziz2, Dock11) as a guanine nucleotide exchange factor (GEF) for Cdc42 and demonstrated that it activated the formation of filopodia. Since its expression pattern is restricted in immune tissues and Rho GTPases such as Cdc42 function in B cell deve...
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| Publicado no: | Immun Ageing |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4343071/ https://ncbi.nlm.nih.gov/pubmed/25729399 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0028-x |
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