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The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation

We originally cloned and identified murine Zizimin2 (Ziz2, Dock11) as a guanine nucleotide exchange factor (GEF) for Cdc42 and demonstrated that it activated the formation of filopodia. Since its expression pattern is restricted in immune tissues and Rho GTPases such as Cdc42 function in B cell deve...

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Bibliographische Detailangaben
Veröffentlicht in:Immun Ageing
Hauptverfasser: Matsuda, Takenori, Yanase, Shougo, Takaoka, Akinori, Maruyama, Mitsuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343071/
https://ncbi.nlm.nih.gov/pubmed/25729399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0028-x
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