The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation

We originally cloned and identified murine Zizimin2 (Ziz2, Dock11) as a guanine nucleotide exchange factor (GEF) for Cdc42 and demonstrated that it activated the formation of filopodia. Since its expression pattern is restricted in immune tissues and Rho GTPases such as Cdc42 function in B cell deve...

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Bibliografiske detaljer
Udgivet i:Immun Ageing
Main Authors: Matsuda, Takenori, Yanase, Shougo, Takaoka, Akinori, Maruyama, Mitsuo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343071/
https://ncbi.nlm.nih.gov/pubmed/25729399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-015-0028-x
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