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Evidence That Tetrodotoxin and Saxitoxin Act at a Metal Cation Binding Site in the Sodium Channels of Nerve Membrane

The effects of monovalent, divalent, and trivalent cations on the binding of tetrodotoxin and saxitoxin to intact nerves and to a preparation of solubilized nerve membranes have been examined. All eight divalent and trivalent cations tested, and the monovalent ions Li(+), Tl(+), and H(+) appear to c...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Henderson, R., Ritchie, J. M., Strichartz, G. R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1974
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434301/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4530274/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.10.3936
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