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Binding to saxitoxin to electrically excitable neuroblastoma cells.

Saxitoxin inhibits the action potential Na+ ionophore of electrically excitable neuroblastoma cells with a KI of 3.7 nM. Binding experiments detect a single class of saturable binding sites with KD = 3.9 nM and a binding capacity of 156 fmol/mg of cell protein (78 sites per micrometer2 of cell surfa...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Catterall, W A, Morrow, C S
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1978
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC411217/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/272638/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.1.218
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