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Tyro3, Axl, and Mertk Receptor Signaling in Inflammatory Bowel Disease and Colitis-associated Cancer

Three receptor tyrosine kinases, Tyro3, Axl, and Mertk (TAM) and their ligands Gas6 and Protein S, have emerged as potent negative regulators of innate immune responses. A number of studies using genetic ablation of TAM loci in mice have elucidated the mechanism of TAM engagement and function during...

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Détails bibliographiques
Publié dans:Inflamm Bowel Dis
Auteurs principaux: Rothlin, Carla V., Leighton, Jonathan A., Ghosh, Sourav
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4343000/
https://ncbi.nlm.nih.gov/pubmed/24846720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000000050
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