The Effects of Streptomycin or Dihydrostreptomycin Binding to 16S RNA or to 30S Ribosomal Subunits

Evidence is presented suggesting that streptomycin binds to 16S RNA or to 30S ribosomal subunits at the same topographical site located on the RNA chain. The equally bactericidal dihydrostreptomycin binds to the same site as streptomycin but with lower affinity. The effect of drug binding to 16S RNA...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Garvin, Robert T., Biswas, Debajit K., Gorini, Luigi
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1974
Témata:	Biological Sciences: Biochemistry
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC434274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4139702/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.71.10.3814
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